1 edition of Glucagon, physiology, pathophysiology, and morphology of the pancreatic A-cells found in the catalog.
Includes bibliographies and index.
|The Physical Object|
|Pagination||xvi, 61 p. :|
|Number of Pages||46|
nodata File Size: 9MB.
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That is, glucagon has the effect of increasing blood glucose levels. Chapter Review The pancreas has both exocrine and endocrine functions. The alpha cell produces the hormone glucagon and makes up approximately 20 percent of each islet. The Cellular Level and morphology of the pancreatic A-cells Organization• Although insulin deficiency is clearly the major defect in type 1 diabetes mellitus, there is considerable evidence that aberrant secretion of glucagon contributes to the metabolic derangements seen in this important disease.
This form of diabetes accounts for less than five percent of all diabetes cases. In the absence of insulin, these transport proteins are normally recycled slowly between the cell membrane and cell interior. Also shown are the exocrine acinar cells. Cancers of alpha cells glucagonomas are one situation known to cause excessive glucagon secretion.
Alpha cells of the pancreas produce glucagon, while beta cells produce insulin. Later, when blood glucose levels begin to fall, glucagon is secreted and acts on hepatocytes to activate the enzymes that depolymerize glycogen and release glucose.
Uncontrolled diabetes can also lead to a dangerous form of metabolic acidosis called ketoacidosis. Fluid, Electrolyte, and Acid-Base Balance•
The treatment of diabetes depends on the type, the severity of the condition, and the ability of the patient to make lifestyle changes.