2 edition of Cellular calcium and phosphate transport in health and disease found in the catalog.
Includes bibliographies and index.
|The Physical Object|
|Pagination||xvi, 87 p. :|
|Number of Pages||79|
|3||Progress in clinical and biological research ;|
nodata File Size: 2MB.
Maintenance of normal serum phosphorus levels is primarily achieved through a tightly regulated process of Pi reabsorption from the glomerular filtrate.
The mineral transport can be with downhill or against uphill a gradient. The serum calcium concentration can be abnormally high, as in malignancy and primary hyperparathyroidism, or abnormally low as it is in renal failure and hypoparathyroidism.
Department of Physiology and Cell Biology Washington University School of Medicine St. Exit from the cell is regulated by membrane structures similar to those that mediate entry.
This condenser function of the cell membrane plays an active role in disease prevention. Whereas PTHrP 1-139 is quite similar to PTHrP 1-141, PTHRP 1-173 completely diverges from both at its own carboxy terminus.
Gain-of-function mutations of LRP-5 cause a high bone density phenotype and loss-of-function mutations cause the osteoporosis-glioma syndrome 23.
Hence, the vitamin D hormonal system consists of multiple forms, ranging from cutaneous precursors or dietary components to the most active metabolite, 1,25 OH 2D, which acts upon the target organ receptors to maintain calcium homeostasis and bone health. In MS, the loss of the myelin sheath demyelination leads to a disruption in the ability of the nerves to conduct electrical impulses.
showed that an acute inhibition of the CaSR does not alter NaCl reabsorption or the transepithelial potential difference but increased the permeability to calcium of the paracellular pathway.
X-linked hypophosphatemic rickets XLH PHEX geneautosomal dominant hypophosphatemic rickets ADHR FGF23 geneautosomal recessive hypophosphatemic rickets ARHR DMP1, ENPP1, FAM20C genesand tumor-induced osteomalacia TIO are associated with excessive FGF23 43. Pi is reabsorbed via three sodium phosphate cotransporters: Npt2a, Npt2c and PiT-2. Deftos, LJ: Hypercalcemia in malignant and inflammatory diseases. It has already been demonstrated that the adaptation of intestinal calcium absorption of rats on a low calcium diet can be eliminated by thyroparathyoidectomy plus parathyroid hormone administration.
Bone mass is acquired up to the fourth decade, with a rapid phase during adolescent growth. Bone consists of a mineral phase and an organic phase Table 5 2. Use of any information is solely at the user's own risk. On the other hand, corticosteroid therapy may result in many harmful side effects that become more prevalent over the course of treatment.
GI Disorders In European clinics, Ca-AEP is used in the treatment of gastritis, duodenitis colitis, ulcer pain and other disturbances of the GI tract.
The power to reduce: pyridine nucleotides—small molecules with a multitude of functions.
Calcium is rapidly and reversibly bound to the calmodulin-actin-myosin I complex.
Diabetic retinopathy has been prevented and reversed by treatment with Ca-AEP.
Unabsorbed calcium passes into the feces, which also contains the small amount of calcium secreted into the GI tract.