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5 edition of The effect of microtubule inhibitors on chromosome cycles of Xenopus laevis blastomeres found in the catalog.

The effect of microtubule inhibitors on chromosome cycles of Xenopus laevis blastomeres

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      • Thesis (M.Sc.)--University of Toronto, 1989.Includes bibliographical references.

        StatementNational Library of Canada
        PublishersNational Library of Canada
        Classifications
        LC Classifications1990
        The Physical Object
        Paginationxvi, 123 p. :
        Number of Pages53
        ID Numbers
        ISBN 100315565098
        Series
        1
        2Canadian theses = Thèses canadiennes
        3

        nodata File Size: 2MB.


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Both Cdc2 and Cdk2 are targets of XChk1 signaling Figure. In contrast, kinetochore fibers, which have uniform microtubule polarity, may flux by different mechanisms. All studied mRNAs are distributed evenly among the set of animal as well as vegetal blastomeres. 1997,Collart, Titration of four replication factors is essential for the Xenopus laevis midblastula transition. Abstract Within minutes of the induction of DNA double-strand breaks in somatic cells, histone H2AX becomes phosphorylated in the serine 139 residue at the damage site.

Microtubule Dependence of Chromosome Cycles inXenopus laevisBlastomeres under the Influence of a DNA Synthesis Inhibitor, Aphidicolin

Involvement of Chk1 kinase in prophase I arrest of Xenopus embryos. The homozygous mothers exhibit no defects other than the inviability of their progeny,suggesting the existence of a specific factor required for the early embryonic cell cycle in a vertebrate.

INTRODUCTION Genome size varies across species and generally correlates with various body composition parameters at wider scales including whole body, organ, tissue, cell, and nuclear sizes.

The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. D Metaphase I left and metaphase II right chromosome spreads double-stained with Sytox orange and anti—Aur-B. When DNA replication is blocked with aphidicolin or DNA is damaged by UV-irradiationextracts supplemented with sperm nuclei arrest with low Cdc2 activity that is insufficient to induce mitosis. After washing, the blot was exposed to Kodak XAR5 film.